Citalopram-induced major depression in a patient with panic disorder - a case report.

نویسندگان

  • Peter Hofmann
  • Rupert Conrad
چکیده

Citalopram represents a very selective drug inhibiting the reuptake of serotonin 3,400 times more than that of norepinephrine (Hiemke & Härter 2000). It has almost no affinity for acetylcholine, histamine, norepinephrine, dopamine, γ-aminobutyric acid (GABA) or opiate receptors (Hiemke & Härter 2000). In a dose range of 20 to 60 mg/day citalopram has proven to be an effective agent in depression (Keller 2000). Citalopram is also effective in the treatment of panic disorder, especially in a dose of 20 to 30 mg/day (Lepola et al. 1998). The anti-panic effect of citalopram is explained by a deficient serotonergic neurotransmission in panic disorder (Humble & Wistedt 1992).

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عنوان ژورنال:
  • Psychiatria Danubina

دوره 24 1  شماره 

صفحات  -

تاریخ انتشار 2012